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The Symptoms,Causes,Diagnosis,Treatment and Prevention of Coccidioidomycosis







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Dec 1, 2010, 7:41 PM

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Coccidioidomycosis could be a fungal disease caused posadasii.It by Coccidioides immitis or C to be considered endemic in parts of Arizona, California, Nevada, New Mexico, Texas, Utah and northwestern Mexico.It been recognized for people, livestock infected, deer, dogs, moose, fish, mules, cattle, monkeys, kangaroos, wallabies, tigers, bears, badgers, otters and marine mammals.

Coccidioidomycosis Symptoms

Many dogs may be infected subclinically. Key lung infection could possibly be the most common form in dogs that develop in sick. affected animals often have a long-term cough, which may dry moist, or and productive. Fever may be seen, but some dogs have a normal emperature. excessive weight loss and anorexia are common. Open lung inflammation may occur in some animals and may be fatal. Lung lesions, similar to solitary nodules, including those found in humans, can perhaps be seen in some asymptomatic dogs.

Coccidioidomycosis Causes

Disseminated disease can occur with or without obtaining a history of respiratory diseases or concomitant pulmonary symptoms. This type of coccidioidomycosis may be months or years after infection important. The clinical indicators vary with the site, and may be accompanied by non-specific indicators that kind of excessive as persistent or fluctuating fever, depression, anorexia and weight loss. In dogs, Coccidioides spp. most often spread to bone, especially in the appendicular skeleton, and causes lameness and pain. when the vertebrae are involved, it can perhaps be neurological deficits of this kind as ataxia, paresis or paralysis, in addition to back or neck pain. Draining skin nodules, or treatises may be found on the sites of bone involvement. Other sites reported the spread of the lymph nodes, skin, subcutaneous tissue, brain, heart, liver, spleen, kidneys, eyes, testicles and prostate. In contrast to coccidioidomycosis in humans, is characterized by CNS invasion of granulomatous lesions in dogs often as meningitis and seizures are the most common characters. The contribution from the heart and pericardium might end result in heart failure, heart rhythm disturbances, syncope or sudden death. Eye damage include fungal granulomas, anterior uveitis, iritis, retinal detachment and blindness.

Coccidioidomycosis diagnosis

1.Expect 10 to 15% of the people to a long-term pulmonary infection that usually create causes lung nodules or thin-walled pleural cavities.

2.Be alert for meningitis. This could possibly be the worst complication of coccidioidomycosis and is often accompanied by hydrocephalus.

3.Observe to include a fine papular rash skin lesions and erythema (redness of the skin). People with suppressed immune systems also may get pneumonia.

4.Look for the indicators and symptoms of disseminated coccidioidomycosis infection of effects on bone, joints and soft tissues. This may lytic lesions in the bones, keratotic ulcers or subcutaneous abscesses in the skin and severe synovitis and effusion in the joints. Disseminated coccidioidomycosis can virtually affect any organ or plan, including the adrenal glands, GI and urogenital tract, pericardium and peritoneum, if it becomes widespread.

5.Realize that only fifty% of cases of coccidioidomycosis display all indicators of infection. The flu-like symptoms and indicators of chest pain, cough, fatigue, fever and headache and shortness of breath usually occur 7-21 solve a quick trip to publicity and obtaining treatment.


Coccidioidomycosis Treatments

Dogs and cats with clinical coccidioidomycosis are usually treated with antifungal agents. It is not recognized as a variety of animals with the most important respiratory diseases would recover on their own, but developed a significant number of dogs spread disease before the oral antifungal agents were available. For this reason, the treatment was standard practice. There is some debate about this practice, because these treatments can have negative results and should often be given for months. Antifungal treatments that are currently being used in dogs and cats are amphotericin B and azole treatments of this type as ketoconazole, itraconazole and fluconazole. There are several reports of successful treatment of horses with conditions such as type pulmonary coccidioidomycosis or vertebral osteomyelitis. Most animals are treated for at least 6-12 months. In disseminated disease, treatment often continues for one to several years. Relapses could be.

Coccidioidomycosis Prevention

1.Keep the immune system healthy plan. People with poor immune systems are much more opportunistic infections may arrangement of this kind as coccidioidomycosis. HIV copies should be especially diligent to consume well, purchasing a lot of sleep and lowering stress.

2.Continue treatment with antifungal agents for an indefinite period as a secondary prophylaxis when the disease is active. Key to preventing coccidioidomycosis is generally not recommended. A typical treatment is 200 mg orally twice daily or 400 mg itraconazole time fluconazaole every day.

3.Use dust manage to interfere with actions when a huge volume of soil.

4.Stop Coccidioidomycosis propagation from the disposal of dressing or cast material from an infected patient. These materials may be contaminated with Coccidioides spores, although the infection itself is not transmitted directly between people.

5.Educate high-risk individuals to avoid measures. People of African descent and Filipino are pregnant women and people with diabetes or a weakened immune system challenges with respect to threats to coccidioidomycosis and should be avoided, high-risk actions of this type of building, archaeological excavations, together with other excavation.
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